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An unsteady analysis of nonlinear two‐layered 2D model of pulsatile flow through stenosed arteries

    P. K. Mandal Affiliation

Abstract


The effects of red cell concentration and peripheral layer viscosity on physiological characteristics of pulsatile flow in presence of mild stenosis are investigated. The flowing blood is represented by a two‐fluid model, consisting of a core region of suspension of all the erythrocytes assumed to be non‐Newtonian (inhomogeneous Newtonian) and a peripheral plasma layer free from cells of any kind as a Newtonian fluid. In the realm of the flow characteristics of blood the viscosity is taken to be a function of hematocrit in a manner that it varies radially only in the central core characterising its non‐Newtonian behaviour while it remains constant in the plasma region. The arterial wall motion and its effect on local fluid mechanics is also incorporated in the present theoretical study. Finite difference scheme has been used to solve the unsteady Navier‐Stokes equations in cylindrical coordinates assuming axial symmetry under laminar conditions, so that the problem effectively becomes two‐dimensional. The nonlinear terms appearing in the Navier‐Stokes equations governing blood flow are accounted for. Finally, the numerical illustration presented at the end of the paper provides an effective measure of the flux, the resistive impedance and the wall shear stress quantitatively in order to validate the applicability of the present model.


Netiesinio dviejų sluoksnių dvimačio modelio analizę


Santrauka. Straipsnyje ištirti raudonųjų kraujo kūnelių koncentracijos efektai ir periferinio sluoksnio klampumas priklausomai nuo pulsavimo fiziologinių charakteristikų, esant nestipriai stenozei. Tekantis kraujas aprašomas dviejų skysčių modelių, vienas iš jų laikomas neniutoniniu skysčiu, kitas – periferinė plazma, laikoma niutoniniu skysčiu be jokiu ląstelių. Kraujo srauto klampumas yra hematokrito funkcija, kuri keičiasi pagal spindulį neniutoniniame skystyje, o plazmoje nekinta. Į modelio tyrimą įtraukti arterijų sienelių judėjimas ir jo sukelti efektai lokaliajai skysčio mechanikai. Baigtinių skirtumų schema naudojama spręsti nestacionarias Navier‐Stokes lygtis cilindrinėse koordinatėse, kai laminarinės sąlygos tenkina ašinio simetriškumo sąlyga, ir uždavinys yra faktiškai dvimatis. Pateiktas skaitinis eksperimentas patvirtina modelio tinkamumą.



First Published Online: 14 Oct 2010

Keyword : Hematocrit, Stenosis, Inhomogeneous Newtonian, Resistive impedance, Wall shear stress

How to Cite
Mandal, P. K. (2003). An unsteady analysis of nonlinear two‐layered 2D model of pulsatile flow through stenosed arteries. Mathematical Modelling and Analysis, 8(3), 229-246. https://doi.org/10.3846/13926292.2003.9637226
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Sep 30, 2003
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